DSIP can be used nightly for 4-8 weeks during periods of poor sleep, though many people find they need it less frequently as their natural sleep patterns improve. Some users prefer cycling it (4 weeks on, 2 weeks off) to maintain effectiveness, while others use it only during high-stress periods. There's no evidence of tolerance development with consistent use, but periodic breaks help assess whether you still need support.
PubMed: DSIP usage patterns